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Article

Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics.

Acta pharmacologica Sinica - 1 Oct 2011

Bae Jung-woo, Choi Chang-ik, Kim Mi-jeong, Oh Da-hee, Keum Seul-ki, Park Jung-in, Kim Bo-hye, Bang Hye-kyoung, Oh Sung-gon, Kang Byung-sung, Park Hyun-joo, Kim Hae-deun, Ha Ji-hey, Shin Hee-jung, Kim Young-hoon, Na Han-sung, Chung Myeon-woo, Jang Choon-gon, Lee Seok-yong

Abstract excerpt

AIM: CYP2C9 enzyme metabolizes numerous clinically important drugs. The aim of this study is to investigate the frequencies of CYP2C9 genotypes and the effects of selected alleles on losartan pharmacokinetics in a large sample of the Korean population. METHODS: The CYP2C9 gene was genotyped in 1796 healthy Korean subjects. CYP2C9 alleles (CYP2C9*1, *2, *3 and *13 alleles) were measured using polymerase chain...

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Identifiers

PMID: 21841812
DOI: 10.1038/aps.2011.100
PMCID: PMC4010224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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