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Article

Unique quantitative trait loci in synergy permanently improve diastolic dysfunction.

The Canadian journal of cardiology - 1 Oct 2013

Chauvet Cristina, Crespo Kimberley, Shi Yanfen, Gelinas Danielle, Duval Francine, L'Heureux Nathalie, Nattel Stanley, Tardif Jean-Claude, Deng Alan Y

Abstract excerpt

BACKGROUND: Diastolic dysfunction often precedes the onset of diastolic heart failure. We previously demonstrated that diastolic dysfunction and left ventricular hypertrophy (LVH) in Dahl salt-sensitive rats can be ameliorated by quantitative trait loci (QTLs). METHODS: We analyzed cardiac phenotypes of 2 "single" congenic strains, C10S.L33 and C10S.L28, by echocardiography, in which a specific Dahl...

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Source

Identifiers

PMID: 23773896
DOI: 10.1016/j.cjca.2013.03.012

Genes

CCL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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