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Microarray analysis of rat chromosome 2 congenic strains.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 2003

McBride Martin W, Carr Fiona J, Graham Delyth, Anderson Niall H, Clark James S, Lee Wai K, Charchar Fadi J, Brosnan M Julia, Dominiczak Anna F

Abstract excerpt

Human essential hypertension is a complex polygenic trait with underlying genetic components that remain unknown. The stroke-prone spontaneously hypertensive rat (SHRSP) is a model of human essential hypertension, and a number of reproducible blood pressure regulation quantitative trait loci have been found to map to rat chromosome 2. The SP.WKYGla2c* congenic strain was produced by introgressing a region of rat...

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PMID: 12624007
DOI: 10.1161/01.HYP.0000047103.07205.03

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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