Article
Genome scan and congenic strains for blood pressure QTL using Dahl salt-sensitive rats.
Genome research - 1 Jul 1998
Garrett M R, Dene H, Walder R, Zhang Q Y, Cicila G T, Assadnia S, Deng A Y, Rapp J P
Abstract excerpt
An F2 population (n = 151) derived from Dahl salt-sensitive (S) and Lewis rats was raised on a 8% NaCl diet for 9 weeks and analyzed for blood pressure quantitative trait loci (QTL) by use of a whole genome scan. Chromosomes 5 and 10 yielded lod scores for linkage to blood pressure that were significant; chromosomes 1, 2, 3, 8, 16, 17, and 18 gave lod scores suggestive for linkage. Chromosome 7 gave a significant...
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