Article
Genome scan and congenic strains for blood pressure QTL using Dahl salt-sensitive rats.
Genome research - 1 Jul 1998
Garrett M R, Dene H, Walder R, Zhang Q Y, Cicila G T, Assadnia S, Deng A Y, Rapp J P
Abstract excerpt
An F2 population (n = 151) derived from Dahl salt-sensitive (S) and Lewis rats was raised on a 8% NaCl diet for 9 weeks and analyzed for blood pressure quantitative trait loci (QTL) by use of a whole genome scan. Chromosomes 5 and 10 yielded lod scores for linkage to blood pressure that were sign...
Topics
- Animals
- Animals, Congenic
- Body Weight
- Crosses, Genetic
- Genetic Linkage
- Genome
- Genotype
- Hypertension
- Male
- Phenotype
- Quantitative Trait, Heritable
- Rats
- Rats, Inbred BN
- Rats, Inbred Lew
- Rats, Inbred WKY
- Sodium Chloride, Dietary