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Article

Epistatic genetic determinants of blood pressure and mortality in a salt-sensitive hypertension model.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 2009

Cicila George T, Morgan Eric E, Lee Soon Jin, Farms Phyllis, Yerga-Woolwine Shane, Toland Edward J, Ramdath Ramona S, Gopalakrishnan Kathirvel, Bohman Keith, Nestor-Kalinoski Andrea L, Khuder Sadik A, Joe Bina

Abstract excerpt

Although genetic determinants protecting against the development of elevated blood pressure (BP) are well investigated, less is known regarding their impact on longevity. We concomitantly assessed genomic regions of rat chromosomes 3 and 7 (RNO3 and RNO7) carrying genetic determinants of BP without known epistasis, for their independent and combinatorial effects on BP and the presence of genetic determinants of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19255363
DOI: 10.1161/HYPERTENSIONAHA.108.126649
PMCID: PMC2697613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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