Article
Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 2009
Chauvet Cristina, Ménard Annie, Tremblay Johanne, Xiao Chunjie, Shi Yanfen, L'Heureux Nathalie, Cardin Sophie, Tardif Jean-Claude, Nattel Stanley, Deng Alan Y
Abstract excerpt
Animal models emulating essential hypertension are an informative means by which to elucidate the physiological mechanisms and gene-gene interactions underlying blood pressure (BP) regulation. We have localized earlier quantitative trait loci (QTLs) for BP on Chromosome (Chr) 2 of Dahl salt-sensitive (DSS) rats, but their chromosome delineations were too large for gene identification. To advance toward positional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
