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Article

Plzf as a candidate gene predisposing the spontaneously hypertensive rat to hypertension, left ventricular hypertrophy, and interstitial fibrosis.

American journal of hypertension - 1 Jan 2014

Liška František, Mancini Massimiliano, Krupková Michaela, Chylíková Blanka, Křenová Drahomíra, Šeda Ondřej, Šilhavý Jan, Mlejnek Petr, Landa Vladimír, Zídek Václav, d' Amati Giulia, Pravenec Michal, Křen Vladimír

Abstract excerpt

BACKGROUND: The spontaneously hypertensive rat (SHR) is the most widely used model of essential hypertension and is susceptible to left ventricular hypertrophy (LVH) and myocardial fibrosis. Recently, a quantitative trait locus (QTL) that influences heart interstitial fibrosis was mapped to chrom...

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Identifiers

PMID: 23975223
DOI: 10.1093/ajh/hpt156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23975223-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Plzf as a candidate gene predisposing the spontaneously hypertensive rat to hypertension, left ventricular hypertrophy, and interstitial fibrosis.PMID 23975223Read ↗

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