Article
Resistance to H-2-restricted but not to allo-H2-specific graft and cytotoxic T lymphocyte responses in lymphoma mutant.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 1990
Ohlén C, Bastin J, Ljunggren H G, Foster L, Wolpert E, Klein G, Townsend A R, Kärre K
Abstract excerpt
The lymphoma mutant RMA-S escaped graft rejection after transplantation over a minor histocompatibility barrier, whereas it was rejected in H-2 allogeneic mice. The parental control line was rejected in both situations. The mutant, which had been selected against MHC class I molecules retained 5...
Topics
- Cytotoxicity, Immunologic
- Dose-Response Relationship, Immunologic
- Graft Rejection
- H-2 Antigens
- Histocompatibility Antigens
- Lymphoma
- Major Histocompatibility Complex
- Minor Histocompatibility Loci
- Mutation
- Neoplasm Transplantation
- Nucleocapsid Proteins
- Nucleoproteins
- Orthomyxoviridae
- Peptide Fragments