Article
Suppression of H-2b-associated resistance to Friend erythroleukemia virus by a class I gene from the H-2d major histocompatibility complex haplotype.
Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 1991
Polsky D, Lilly F
Abstract excerpt
Mice homozygous for the H-2d haplotype at the major histocompatibility complex are markedly more susceptible to erythroleukemia induction by the Friend isolate of murine leukemia retrovirus (FV) than are congenic mice homozygous for the H-2b haplotype. The resistance conferred by the H-2b haplotype is recessive in this cross, since heterozygous F1 mice are as susceptible as parental strain H-2d homozygotes....
Topics
- Animals
- Chromosome Deletion
- Friend murine leukemia virus
- Genes, MHC Class I
- Genetic Predisposition to Disease
- H-2 Antigens
- Haplotypes
- Leukemia, Experimental
- Mice
- Mice, Inbred Strains