Article
Tumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene.
The Journal of experimental medicine - 1 Jan 1993
Franksson L, George E, Powis S, Butcher G, Howard J, Kärre K
Abstract excerpt
Presentation of antigenic peptides by major histocompatibility complex (MHC) class I molecules requires MHC-encoded molecules of the adenosine triphosphate binding cassette (ABC) family. Defects in these proteins represent a potential risk, since they are essential links in the machinery of T cell-mediated surveillance which continuously scrutinizes peptide samples of cellular proteins. Nevertheless, transfection...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
