Article
Associations between prefrontal γ-aminobutyric acid concentration and the tryptophan hydroxylase isoform 2 gene, a panic disorder risk allele in women.
The international journal of neuropsychopharmacology - 1 Sept 2013
Preuss Nora, Salehi Basira, van der Veen Jan Willem, Shen Jun, Drevets Wayne C, Hodgkinson Colin, Goldman David, Hasler Gregor
Abstract excerpt
Associations between the central serotonergic and γ-aminobutyric acid (GABA) systems play key roles in the prefrontal cortical regulation of emotion and cognition and in the pathophysiology and pharmacotherapy of highly prevalent psychiatric disorders. The goal of this study was to test the effects of common variants of the tryptophan hydroxylase isoform 2 (TPH2) gene on GABA concentration in the prefrontal...
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