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Article

Impact of tryptophan hydroxylase 2 G-703T polymorphism on anger-related personality traits and orbitofrontal cortex.

Behavioural brain research - 16 May 2012

Yoon Ho-Kyoung, Lee Heon-Jeong, Kim Leen, Lee Min-Soo, Ham Byung-Joo

Abstract excerpt

Genetic variation in human tryptophan hydroxylase 2 (TPH2) influences TPH enzymatic activity and is associated with emotion-related traits and mood disorders. The present study investigated the effect of the TPH2 G-703T polymorphism on regional brain volume, assessed using voxel-based morphometry...

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Source

Identifiers

PMID: 22649797
DOI: 10.1016/j.bbr.2012.03.001

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22649797-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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