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Article

The association between serotonin-related gene polymorphisms and panic disorder.

Journal of anxiety disorders - 1 Dec 2008

Yoon Ho-Kyoung, Yang Jong-Chul, Lee Heon-Jeong, Kim Yong-Ku

Abstract excerpt

Dysfunction of the serotonergic system has been hypothesized to play an important role in panic disorder. We investigated the 5-HT2A receptor (5HTR2A) and tryptophan hydroxylase (TPH) genes for an association with panic disorder (PD). Patients with PD (n=107) and control subjects (n=161) were genotyped for 5HTR2A 1438A/G, 5HTR2A 102T/C, and TPH218 A/C. The severity of their symptoms was measured using the...

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Source

Identifiers

PMID: 18436425
DOI: 10.1016/j.janxdis.2008.03.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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