Article
Asymmetry of prefrontal cortex activities and catechol-O-methyltransferase Val158Met genotype in patients with panic disorder during a verbal fluency task: near-infrared spectroscopy study.
Neuroscience letters - 6 Mar 2009
Tanii Hisashi, Nishimura Yukika, Inoue Ken, Koshimizu Hiroyuki, Matsumoto Ryusuke, Takami Tetsuhei, Hara Naomi, Nishida Atsushi, Okada Motohiro, Kaiya Hisanobu, Okazaki Yuji
Abstract excerpt
We examined the relationship between the catechol-O-methyltransferase (COMT) Val158Met genotype and frontal lobe function by using multi-channel near-infrared spectroscopy (NIRS). The present study investigated oxygenated ([oxy-Hb]) and deoxygenated ([deoxy-Hb]) hemoglobin concentration changes during the performance of a verbal fluency task in the frontal region of 71 patients with panic disorder (PD). The...
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