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Article

A tryptophan hydroxylase 2 gene polymorphism is associated with panic disorder.

Behavior genetics - 1 Mar 2009

Kim Yong-Ku, Lee Heon-Jeong, Yang Jong-Chul, Hwang Jung-A, Yoon Ho-Kyoung

Abstract excerpt

Panic disorder (PD) is a complex and heterogeneous psychiatric condition. Dysfunction within the serotonergic system has been hypothesized to play an important role in PD. The novel brain-specific serotonin synthesizing enzyme, tryptophan hydroxylase 2 (TPH2), which represents the rate-limiting enzyme of serotonin production in the brain, may therefore be of particular importance in PD. We investigated the TPH2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19132526
DOI: 10.1007/s10519-008-9254-8

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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