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Article

Association of variants in IL2RA with progression of joint destruction in rheumatoid arthritis.

Arthritis and rheumatism - 1 Jul 2013

Knevel R, de Rooy D P C, Zhernakova A, Gröndal G, Krabben A, Steinsson K, Wijmenga C, Cavet G, Toes R E M, Huizinga T W J, Gregersen P K, van der Helm-van Mil A H M

Abstract excerpt

OBJECTIVE: Heritability studies have suggested an important role of genetic predisposition in the progression of joint destruction in rheumatoid arthritis (RA); the heritability is estimated at 45-58%. Several single-nucleotide polymorphisms (SNPs) have been identified as being associated with RA susceptibility. Our objective was to study the association of several of these loci with progression of joint...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23529819
DOI: 10.1002/art.37938

Genes

AFF3
BLK
RBM17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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