Article
FCRL3 gene polymorphisms contribute to the radiographic severity rather than susceptibility of rheumatoid arthritis.
Human immunology - 1 May 2012
Han Seung Woo, Sa Keum Hee, Kim Sung Il, Lee Sang Il, Park Yong Wook, Lee Shin Seok, Yoo Wan Hee, Kang Jin Young, Soe Jae Seok, Nam Eon Jeong, Lee Jongmin, Park Jae Yong, Kang Young Mo
Abstract excerpt
The ethnic heterogeneity and genetic complexity of rheumatoid arthritis (RA) have produced inconsistent results in previous genetic association studies concerning FCRL3. This study sought to delineate the association between the FCRL3 gene polymorphisms and susceptibility to RA and to investigate the effects of the polymorphisms on the progression of joint destruction in RA. RA patients (n = 377) and healthy...
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