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Article

Association of IL-2RA and IL-2RB genes with erosive status in early rheumatoid arthritis patients (ESPOIR and RMP cohorts).

Joint bone spine - 1 May 2014

Ruyssen-Witrand Adeline, Lukas Cedric, Nigon Delphine, Dawidowicz Karen, Morel Jacques, Sibilia Jean, Jamard Bénédicte, Cambon-Thomsen Anne, Cantagrel Alain, Dieudé Philippe, Constantin Arnaud

Abstract excerpt

OBJECTIVES: To assess the impact of single nucleotide polymorphisms (SNPs) in IL-2RA (rs2104286) and IL-2RB (rs743777 and rs3218253) genes on the risk of erosions in rheumatoid arthritis (RA) patients. METHODS: This work is derived from 2 prospective cohorts of early RA: ESPOIR (n = 439) and RMP (n = 180). The proportions of patients with erosions at baseline and 1 year according to the genotypes of IL2RA...

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Share to Arthritis, Rheumatoid
Share to Autoantibodies
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Share to Interleukin-2 Receptor alpha Subunit
Share to Peptides, Cyclic
Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 24200909
DOI: 10.1016/j.jbspin.2013.10.002

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