Article
Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Mar 2010
Scherer Hans Ulrich, van der Linden Michael P M, Kurreeman Fina A S, Stoeken-Rijsbergen Gerrie, Cessie Saskia le, Huizinga Tom W J, van der Helm-van Mil Annette H, Toes René E M
Abstract excerpt
BACKGROUND: Two novel genetic polymorphisms on chromosome 6q23 are associated with susceptibility to rheumatoid arthritis (RA). Both polymorphisms (rs6920220 and rs10499194) reside in a region close to the gene encoding tumour necrosis factor alpha-induced protein 3 (TNFAIP3). TNFAIP3 is a negati...
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