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Article

Association of the IL4R single-nucleotide polymorphism I50V with rapidly erosive rheumatoid arthritis.

Arthritis and rheumatism - 1 May 2006

Prots Iryna, Skapenko Alla, Wendler Jörg, Mattyasovszky Stefan, Yoné Clarisse L, Spriewald Bernd, Burkhardt Harald, Rau Rolf, Kalden Joachim R, Lipsky Peter E, Schulze-Koops Hendrik

Abstract excerpt

OBJECTIVE: To examine whether single-nucleotide polymorphisms (SNPs) of the interleukin-4 receptor gene IL4R influence susceptibility to, or radiographic progression in, rheumatoid arthritis (RA). METHODS: The contribution of 2 SNPs (I50V and Q551R) in the coding region of IL4R to RA susceptibility was analyzed by allele-specific polymerase chain reaction in a case-control study of 471 RA patients and 371 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-4 Receptor alpha Subunit

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 16646030
DOI: 10.1002/art.21832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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