Article
A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis.
Arthritis research & therapy - 8 Jan 2015
van Steenbergen Hanna W, Rodríguez-Rodríguez Luis, Berglin Ewa, Zhernakova Alexandra, Knevel Rachel, Ivorra-Cortés Jose, Huizinga Tom W J, Fernández-Gutiérrez Benjamin, Gregersen Peter K, Rantapää-Dahlqvist Solbritt, van der Helm-van Mil Annette H M
Abstract excerpt
INTRODUCTION: The severity of joint damage progression in rheumatoid arthritis (RA) is heritable. Several genetic variants have been identified, but together explain only part of the total genetic effect. Variants in Interleukin-6 (IL-6), Interleukin-10 (IL-10), C5-TRAF1, and Fc-receptor-like-3 (FCRL3) have been described to associate with radiographic progression, but results of different studies were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
