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Article

Increased thymic development of regulatory T cells in NOD mice is functionally dissociated from type I diabetes susceptibility.

European journal of immunology - 1 May 2013

Tellier Julie, Andrianjaka Andry, Vicente Rita, Thiault Nicolas, Enault Geneviève, Garchon Henri-Jean, van Meerwijk Joost P M, Romagnoli Paola

Abstract excerpt

Regulatory T (Treg) lymphocytes play a central role in the control of autoimmune pathology. Any alteration in Treg-cell biology in mouse strains used for the study of these disorders therefore raises the question of its direct link with disease susceptibility. Paradoxically, in non-obese diabetic (NOD) mice increased numbers of Treg cells develop in the thymus. In this report we identify a locus of <7 Mbp that...

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Identifiers

PMID: 23400928
DOI: 10.1002/eji.201243142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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