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Article

The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2022

Lombard-Vadnais Félix, Collin Roxanne, Daudelin Jean-François, Chabot-Roy Geneviève, Labrecque Nathalie, Lesage Sylvie

Abstract excerpt

Type 1 diabetes is an autoimmune disease characterized by pancreatic β cell destruction. It is a complex genetic trait driven by >30 genetic loci with parallels between humans and mice. The NOD mouse spontaneously develops autoimmune diabetes and is widely used to identify insulin-dependent diabetes (Idd) genetic loci linked to diabetes susceptibility. Although many Idd loci have been extensively studied, the...

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Identifiers

PMID: 35039332
DOI: 10.4049/jimmunol.2100456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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