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Article

NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes.

European journal of immunology - 1 Dec 2011

Simoni Yannick, Gautron Anne-Sophie, Beaudoin Lucie, Bui Linh-Chi, Michel Marie-Laure, Coumoul Xavier, Eberl Gérard, Leite-de-Moraes Maria, Lehuen Agnès

Abstract excerpt

Invariant natural killer T (iNKT) cells are a distinct lineage of innate-like T lymphocytes and converging studies in mouse models have demonstrated the protective role of iNKT cells in the development of type 1 diabetes. Recently, a new subset of iNKT cells, producing high levels of the pro-inflammatory cytokine IL-17, has been identified (iNKT17 cells). Since this cytokine has been implicated in several...

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PMID: 22002883
DOI: 10.1002/eji.201141751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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