Article
Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.
Journal of autoimmunity - 1 Sept 2013
Bour-Jordan Hélène, Thompson Heather L, Giampaolo Jennifer R, Davini Dan, Rosenthal Wendy, Bluestone Jeffrey A
Abstract excerpt
The non-obese diabetic (NOD) mouse is susceptible to the development of autoimmune diabetes but also multiple other autoimmune diseases. Over twenty susceptibility loci linked to diabetes have been identified in NOD mice and progress has been made in the definition of candidate genes at many of these loci (termed Idd for insulin-dependent diabetes). The susceptibility to multiple autoimmune diseases in the NOD...
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