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Article

Decoding asthma: translating genetic variation in IL33 and IL1RL1 into disease pathophysiology.

The Journal of allergy and clinical immunology - 1 Mar 2013

Grotenboer Néomi S, Ketelaar Maria E, Koppelman Gerard H, Nawijn Martijn C

Abstract excerpt

Asthma is a complex disease that results from the interaction between genetic predisposition and environmental factors. Recently, genome-wide association studies have identified a number of genes that significantly contribute to asthma. Two of these genes, IL33 and IL-1 receptor-like 1 (IL1RL1), act in one signal transduction pathway. IL33 encodes a cytokine released on damage of cells, whereas IL1RL1 encodes...

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Source

Identifiers

PMID: 23380221
DOI: 10.1016/j.jaci.2012.11.028

Genes

RORA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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