Article
The genetics of asthma and allergic disease: a 21st century perspective.
Immunological reviews - 1 Jul 2011
Ober Carole, Yao Tsung-Chieh
Abstract excerpt
Asthma and allergy are common conditions with complex etiologies involving both genetic and environmental contributions. Recent genome-wide association studies (GWAS) and meta-analyses of GWAS have begun to shed light on both common and distinct pathways that contribute to asthma and allergic diseases. Associations with variation in genes encoding the epithelial cell-derived cytokines, interleukin-33 (IL-33) and...
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