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Article

Genetics of Interleukin 1 Receptor-Like 1 in Immune and Inflammatory Diseases

16 Nov 2010

Abstract excerpt

Interleukin 1 receptor-like 1 (IL1RL1) is gaining in recognition due to its involvement in immune/inflammatory disorders. Well-designed animal studies have shown its critical role in experimental allergic inflammation and human in vitro studies have consistently demonstrated its up-regulation in several conditions such as asthma and rheumatoid arthritis. The ligand for IL1RL1 is IL33 which emerged as playing an...

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PMID: 21629437
DOI: 10.2174/138920210793360907

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