Article
New dog and new tricks: evolving roles for IL-33 in type 2 immunity
23 Mar 2015
Abstract excerpt
IL-33 is a more recently identified member of the IL-1 cytokine family, expressed in the nucleus of epithelial cells and released into the extracellular space following tissue damage. The impact of IL-33 as a regulator of the adaptive immune response has been studied extensively, with an understood role for IL-33 in the effector functions of CD4(+) Th2 cells. IL-33, however, is now being shown to initiate the...
Topics
Join the communities discussing this publication.