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Article

IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population.

International journal of immunogenetics - 1 Apr 2017

Queiroz G A, Costa R S, Alcantara-Neves N M, Nunes de Oliveira Costa G, Barreto M L, Carneiro V L, Figueiredo C A

Abstract excerpt

Atopic asthma is a chronic inflammatory disease in airways resulting from genetic and environmental factors, characterized by production of the Th2 cytokines interleukin-4 (IL-4), interleukin-5 (IL-5) and interleukin-13 (IL-13). Interleukin-33 (IL-33) appears to be a potent inducer of Th2 immune response. This occurs when IL-33 binds and activates its receptor, the membrane ST2 (ST2L) in mast cells, dendritic...

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Identifiers

PMID: 28266165
DOI: 10.1111/iji.12306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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