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Article

IRGM variants and susceptibility to inflammatory bowel disease in the German population.

PloS one - 1 Jan 2013

Glas Jürgen, Seiderer Julia, Bues Stephanie, Stallhofer Johannes, Fries Christoph, Olszak Torsten, Tsekeri Eleni, Wetzke Martin, Beigel Florian, Steib Christian, Friedrich Matthias, Göke Burkhard, Diegelmann Julia, Czamara Darina, Brand Stephan

Abstract excerpt

BACKGROUND & AIMS: Genome-wide association studies identified the autophagy gene IRGM to be strongly associated with Crohn's disease (CD) but its impact in ulcerative colitis (UC), its phenotypic effects and potential epistatic interactions with other IBD susceptibility genes are less clear which we therefore analyzed in this study. METHODOLOGY/PRINCIPAL FINDINGS: Genomic DNA from 2060 individuals including 817...

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Source

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Identifiers

PMID: 23365659
DOI: 10.1371/journal.pone.0054338
PMCID: PMC3554777

Genes

IRGM
NOD2

Variants

rs13371189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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