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Associations between genetic variants in the IRGM gene and inflammatory bowel diseases in the Korean population.

Inflammatory bowel diseases - 1 Jan 2013

Moon Chang Mo, Shin Dong-Jik, Kim Seung Won, Son Nak-Hoon, Park Ahram, Park Boram, Jung Eun Suk, Kim Eun Soo, Hong Sung Pil, Kim Tae Il, Kim Won Ho, Cheon Jae Hee

Abstract excerpt

BACKGROUND: Recent European ancestry genome-wide association studies have identified genetic variants of IRGM as significant susceptibility loci for Crohn's disease (CD). Therefore, we investigated whether genetic variants of IRGM confer genetic susceptibility to CD or ulcerative colitis (UC) and evaluated the genotype-phenotype associations in the Korean population. METHODS: This study included 510 inflammatory...

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Identifiers

PMID: 22508677
DOI: 10.1002/ibd.22972

Genes

IRGM

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