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Article

Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.

Inflammatory bowel diseases - 1 Jun 2011

Henckaerts Liesbet, Cleynen Isabelle, Brinar Marko, John Jestinah Mahachie, Van Steen Kristel, Rutgeerts Paul, Vermeire Séverine

Abstract excerpt

BACKGROUND: The autophagy pathway has been linked with Crohn's disease (CD) through association of the ATG16L1 and IRGM genes with susceptibility for CD, and also to the Nod2 pathway, involved in CD. Our aim was to investigate polymorphisms in selected autophagy genes for their association with s...

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Source

Identifiers

PMID: 21560199
DOI: 10.1002/ibd.21486

Genes

ULK1
IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21560199-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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