The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

doi:10.1111/j.1572-0241.2007.01694.x

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Article

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

The American journal of gastroenterology - 1 Mar 2008

Glas Jürgen, Konrad Astrid, Schmechel Silke, Dambacher Julia, Seiderer Julia, Schroff Frieder, Wetzke Martin, Roeske Darina, Török Helga-Paula, Tonenchi Laurian, Pfennig Simone, Haller Dirk, Griga Thomas, Klein Wolfram, Epplen Jörg T, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Mussack Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Brand Stephan

Abstract excerpt

OBJECTIVES: We analyzed ATG16L1, a recently identified Crohn's disease (CD) susceptibility gene, in a large cohort with inflammatory bowel disease (IBD) including potential interactions with other IBD genes as well as factors regulating its gene expression. METHODS: Genomic DNA from 2,890 Caucasians including 768 patients with CD, 507 patients with ulcerative colitis (UC), and 1,615 healthy controls was analyzed...

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PMID: 18162085
DOI: 10.1111/j.1572-0241.2007.01694.x

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NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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