Article
Association between variants of the autophagy related gene--IRGM and susceptibility to Crohn's disease and ulcerative colitis: a meta-analysis.
PloS one - 1 Jan 2013
Lu Xiao Cheng, Tao Yi, Wu Chen, Zhao Peng Lai, Li Kai, Zheng Jin Yu, Li Li Xin
Abstract excerpt
BACKGROUND: Polymorphisms in immunity-related GTPase family M (IRGM) gene may be associated with inflammatory bowel disease (IBD) by affecting autophagy. However, the genetic association studies on three common variants in IRGM gene (rs13361189, rs4958847 and rs10065172) have shown inconsistent results. METHODOLOGY/ PRINCIPAL FINDINGS: The PubMed and Embase were searched up to June 5, 2013 for studies on the...
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