Article
Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach.
Genes and immunity - 1 Jun 2009
Palomino-Morales R J, Oliver J, Gómez-García M, López-Nevot M A, Rodrigo L, Nieto A, Alizadeh B Z, Martín J
Abstract excerpt
The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC). Our study included 557 CD and 425 UC patients and 672 ethnically matched Spanish controls and a meta-analysis with the data published to date. The polymorphisms were genotyped using predesigned TaqMan single nucleotide polymorphism...
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