Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Among autophagy genes, ATG16L1 but not IRGM is associated with Crohn's disease in Iranians.

Gene - 30 Oct 2018

Teimoori-Toolabi Ladan, Samadpoor Sanaz, Mehrtash Amirhosein, Ghadir Mahdis, Vahedi Homayoon

Abstract excerpt

BACKGROUND: The prevalence of inflammatory bowel diseases is uprising in countries like Iran. Genetic predisposing elements play prominent role in the pathogenesis of Crohn's disease. In this study we studied the role of autophagy genes like IRGM (Immunity related GTPase M) and ATG16L1 (Autophagy related 16 like 1) in the pathogenesis of Crohn's Disease in Iranian patients. METHODS: One hundred thirty-eight...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Autophagy-Related Proteins
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to Genetic Association Studies

Share to GTP-Binding Proteins

Share to Young Adult

Source

Identifiers

PMID: 29960072
DOI: 10.1016/j.gene.2018.06.074

Genes

IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Among autophagy genes, ATG16L1 but not IRGM is associated with Crohn's disease in Iranians.PMID 29960072Read ↗

Association between variants of the autophagy related gene--IRGM and susceptibility to Crohn's disease and ulcerative colitis: a meta-analysis.Semantic proximity Read ↗

Role of autophagy and autophagy genes in inflammatory bowel disease.Semantic proximity Read ↗

Is there a role for Crohn's disease-associated autophagy genes ATG16L1 and IRGM in formation of granulomas?Semantic proximity Read ↗

Genome-wide Association Scanning Highlights Two Autophagy Genes,<i>ATG16L1</i>and<i>IRGM</i>, as Being Significantly Associated with Crohn’s DiseaseSemantic proximity Read ↗

Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease.Semantic proximity Read ↗

Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children.Semantic proximity Read ↗

IRGM variants and susceptibility to inflammatory bowel disease in the German population.Semantic proximity Read ↗

Autophagy and Crohns Disease: At the Crossroads of Infection, Inflammation, Immunity, and CancerSemantic proximity Read ↗

Genetic polymorphisms of ATG16L1 and IRGM genes in Malaysian patients with Crohn's disease.Semantic proximity Read ↗

Autophagy and inflammatory bowel disease: Association between variants of the autophagy-related IRGM gene and susceptibility to Crohn's disease.Semantic proximity Read ↗

Genetic Polymorphisms in Autophagy-Associated Genes in Korean Children With Early-Onset Crohn Disease.Semantic proximity Read ↗

Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.