Article
Moo1 obesity quantitative trait locus in BTBR T+ Itpr3tf/J mice increases food intake.
Physiological genomics - 1 Mar 2013
Karunakaran Subashini, Manji Akiff, Yan Chenhua Serena, Wu Zi-Jun John, Clee Susanne M
Abstract excerpt
The rising prevalence of obesity is one of the greatest health challenges facing the world today. Discovery of genetic factors affecting obesity risk will provide important insight to its etiology that could suggest new therapeutic approaches. We have previously identified the Modifier of obese 1 (Moo1) quantitative trait locus (QTL) in a cross between leptin-deficient BTBR T(+) Itpr3(tf)/J (BTBR) and C57BL/6J...
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