Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

Diabetes - 1 Nov 2000

Stoehr J P, Nadler S T, Schueler K L, Rabaglia M E, Yandell B S, Metz S A, Attie A D

Abstract excerpt

Nonlinear interactions between obesity and genetic risk factors are thought to determine susceptibility to type 2 diabetes. We used genetic obesity as a tool to uncover latent differences in diabetes susceptibility between two mouse strains, C57BL/6J (B6) and BTBR. Although both BTBR and B6 lean...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lod Score
Share to Blood Glucose
Share to Diabetes Mellitus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fasting

Share to Hyperinsulinism

Share to Insulin Resistance

Share to Islets of Langerhans

Share to Mice, Obese

Source

Identifiers

PMID: 11078464
DOI: 10.2337/diabetes.49.11.1946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11078464-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.PMID 11078464Read ↗

Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice.Semantic proximity Read ↗

Maternal environment and genotype interact to establish diabesity in mice.Semantic proximity Read ↗

Genetic modifiers of the insulin resistance phenotype in mice.Semantic proximity Read ↗

Gene co-expression modules and type 2 diabetes.Semantic proximity Read ↗

Systems genetics of susceptibility to obesity-induced diabetes in mice.Semantic proximity Read ↗

Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice.Semantic proximity Read ↗

Characterization of epistasis influencing complex spontaneous obesity in the BSB model.Semantic proximity Read ↗

NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds.Semantic proximity Read ↗

QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects.Semantic proximity Read ↗

Identification of diabetes susceptibility loci in db mice by combined quantitative trait loci analysis and haplotype mapping.Semantic proximity Read ↗

Analysis of a genetic region affecting mouse body weightSemantic proximity Read ↗

Multidimensional genome scans identify the combinations of genetic loci linked to diabetes-related phenotypes in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.