Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue

18 Mar 2015

Abstract excerpt

Common variants of human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but the biological explanation for the link has remained obscure. Recent findings suggest that these variants affect the homeobox protein IRX3. Here we report that FTO has a role in white adipose tissue which modifies its response to high-fat feeding. Wild type and Fto-deficient mice were exposed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25782772
DOI: 10.1038/srep09233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissuePMID 25782772Read ↗

Fto-Deficiency Affects the Gene and MicroRNA Expression Involved in Brown Adipogenesis and Browning of White Adipose Tissue in MiceSemantic proximity Read ↗

Obesity-associated variants within FTO form long-range functional connections with IRX3.Semantic proximity Read ↗

Deficiency of <i>Irx5</i> protects mice from diet-induced obesity and associated metabolic abnormalitiesSemantic proximity Read ↗

Obesity and FTO: Changing Focus at a Complex Locus.Semantic proximity Read ↗

Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo.Semantic proximity Read ↗

Role of FTO in Adipocyte Development and Function: Recent InsightsSemantic proximity Read ↗

The role of the FTO (Fat Mass and Obesity Related) locus in regulating body size and composition.Semantic proximity Read ↗

FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?Semantic proximity Read ↗

Inactivation of the Fto gene protects from obesity.Semantic proximity Read ↗

Hypomorphism of Fto and Rpgrip1l causes obesity in mice.Semantic proximity Read ↗

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.Semantic proximity Read ↗

The FTO Gene, Browning of Adipose Tissue and Omega-3 Fatty Acids.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.