Article
A unique genetic defect on chromosome 3 is responsible for juvenile obesity in the Berlin Fat Mouse.
International journal of obesity (2005) - 1 Dec 2010
Neuschl C, Hantschel C, Wagener A, Schmitt A O, Illig T, Brockmann G A
Abstract excerpt
OBJECTIVE: This study aimed at the mapping and estimation of genetic and sex effects contributing to the obese phenotype of the Berlin Fat Mouse Inbred line 860 (BFMI860). This mouse line is predisposed for juvenile obesity. BFMI860 mice accumulate 24% total fat mass at 10 weeks of age under a standard maintenance diet. DESIGN: A total of 471 mice of a (BFMI860 x C57BL/6NCrl) F₂ intercross population were fed a...
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