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Article

Components of selection in the evolution of the influenza virus: linkage effects beat inherent selection.

PLoS pathogens - 1 Dec 2012

Illingworth Christopher J R, Mustonen Ville

Abstract excerpt

The influenza virus is an important human pathogen, with a rapid rate of evolution in the human population. The rate of homologous recombination within genes of influenza is essentially zero. As such, where two alleles within the same gene are in linkage disequilibrium, interference between alleles will occur, whereby selection acting upon one allele has an influence upon the frequency of the other. We here...

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Share to Evolution, Molecular
Share to Gene Frequency
Share to Hemagglutinins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H3N2 Subtype

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Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 23300444
DOI: 10.1371/journal.ppat.1003091
PMCID: PMC3531508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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