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Article

Fitness cost of reassortment in human influenza

7 Nov 2017

Abstract excerpt

Reassortment, which is the exchange of genome sequence between viruses co-infecting a host cell, plays an important role in the evolution of segmented viruses. In the human influenza virus, reassortment happens most frequently between co-existing variants within the same lineage. This process breaks genetic linkage and fitness correlations between viral genome segments, but the resulting net effect on viral...

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PMID: 29112968
DOI: 10.1371/journal.ppat.1006685

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