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Article

Clonal interference in the evolution of influenza.

Genetics - 1 Oct 2012

Strelkowa Natalja, Lässig Michael

Abstract excerpt

The seasonal influenza A virus undergoes rapid evolution to escape human immune response. Adaptive changes occur primarily in antigenic epitopes, the antibody-binding domains of the viral hemagglutinin. This process involves recurrent selective sweeps, in which clusters of simultaneous nucleotide...

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Topics

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Share to Viral Proteins
Share to Genome, Viral
Share to Hemagglutinin Glycoproteins, Influenza Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H3N2 Subtype

Share to Influenza, Human

Share to Models, Theoretical

Share to Mutation Rate

Share to Selection, Genetic

Source

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Identifiers

PMID: 22851649
DOI: 10.1534/genetics.112.143396
PMCID: PMC3454888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22851649-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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