Article
The effects of linkage on comparative estimators of selection.
BMC evolutionary biology - 7 Nov 2013
Chan Carmen H S, Hamblin Steven, Tanaka Mark M
Abstract excerpt
BACKGROUND: A major goal of molecular evolution is to determine how natural selection has shaped the evolution of a gene. One approach taken by methods such as KA/KS and the McDonald-Kreitman (MK) test is to compare the frequency of non-synonymous and synonymous changes. These methods, however, r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
