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Identifying Selection in the Within-Host Evolution of Influenza Using Viral Sequence Data

31 Jul 2014

Abstract excerpt

The within-host evolution of influenza is a vital component of its epidemiology. A question of particular interest is the role that selection plays in shaping the viral population over the course of a single infection. We here describe a method to measure selection acting upon the influenza virus within an individual host, based upon time-resolved genome sequence data from an infection. Analysing sequence data...

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PMID: 25080215
DOI: 10.1371/journal.pcbi.1003755

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