Article
Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival.
Journal of the National Cancer Institute - 20 Feb 2013
Gamazon Eric R, Pinto Navin, Konkashbaev Anuar, Im Hae Kyung, Diskin Sharon J, London Wendy B, Maris John M, Dolan M Eileen, Cox Nancy J, Cohn Susan L
Abstract excerpt
BACKGROUND: Black patients with neuroblastoma have a higher prevalence of high-risk disease and worse outcome than white patients. We sought to investigate the relationship between genetic variation and the disparities in survival observed in neuroblastoma. METHODS: The analytic cohort was composed of 2709 patients. Principal components were used to assign patients to genomic ethnic clusters for survival...
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