Article
Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias.
Journal of the National Cancer Institute - 19 Jul 2000
Wacholder S, Rothman N, Caporaso N
Abstract excerpt
BACKGROUND: Some critics argue that bias from population stratification (the mixture of individuals from heterogeneous genetic backgrounds) undermines the credibility of epidemiologic studies designed to estimate the association between a genotype and the risk of disease. We investigated the degree of bias likely from population stratification in U.S. studies of cancer among non-Hispanic Caucasians of European...
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