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Article

Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa.

Carcinogenesis - 1 Dec 2011

Bye Hannah, Prescott Natalie J, Matejcic Marco, Rose Elizabeth, Lewis Cathryn M, Parker M Iqbal, Mathew Christopher G

Abstract excerpt

Genetic variants in multiple cellular pathways have been associated with an altered risk of oesophageal cancer. In this study, eight genes previously associated with an altered risk of oesophageal squamous cell carcinoma (OSCC) in European or Asian populations were investigated in two South African populations. We genotyped 12 single-nucleotide polymorphisms and one insertion/deletion variant in 1463 individuals...

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Source

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Identifiers

PMID: 21926110
DOI: 10.1093/carcin/bgr211
PMCID: PMC3220606

Genes

CASP8
ALDH2
FAS
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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