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Article

Replication of neuroblastoma SNP association at the BARD1 locus in African-Americans.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2012

Latorre Valeria, Diskin Sharon J, Diamond Maura A, Zhang Haitao, Hakonarson Hakon, Maris John M, Devoto Marcella

Abstract excerpt

BACKGROUND: Neuroblastoma is an often fatal pediatric cancer more frequent in European-American than African-American children. African-American children, however, are at higher risk for the more severe form of neuroblastoma and have worse overall survival than European-American children. Genome-wide association studies (GWAS) have identified several single-nucleotide polymorphisms (SNP) associated to...

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Source

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Identifiers

PMID: 22328350
DOI: 10.1158/1055-9965.EPI-11-0830
PMCID: PMC3319325

Genes

BARD1
LMO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of neuroblastoma SNP association at the BARD1 locus in African-Americans.PMID 22328350Read ↗

Genetic Analysis in African American Children Supports Ancestry-Specific Neuroblastoma Susceptibility.Semantic proximity Read ↗

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.Semantic proximity Read ↗

Fine mapping of 2q35 high-risk neuroblastoma locus reveals independent functional risk variants and suggests full-length BARD1 as tumor-suppressor.Semantic proximity Read ↗

Replication of GWAS-identified neuroblastoma risk loci strengthens the role of BARD1 and affirms the cumulative effect of genetic variations on disease susceptibility.Semantic proximity Read ↗

The Association between GWAS-identified BARD1 Gene SNPs and Neuroblastoma Susceptibility in a Southern Chinese Population.Semantic proximity Read ↗

<i>BARD1</i> germline variants induce haploinsufficiency and DNA repair defects in neuroblastomaSemantic proximity Read ↗

A genome-wide association study in Chinese children identifies and functionally validates 5q31.1 as a neuroblastoma susceptibility locusSemantic proximity Read ↗

Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.Semantic proximity Read ↗

Phenotype restricted genome-wide association study using a gene-centric approach identifies three low-risk neuroblastoma susceptibility Loci.Semantic proximity Read ↗

Integrative genomics identifies LMO1 as a neuroblastoma oncogene.Semantic proximity Read ↗

Candidate Gene Association Analysis of Neuroblastoma in Chinese Children Strengthens the Role of LMO1.Semantic proximity Read ↗

Correlation of BARD1 gene polymorphisms with risk of neuroblastoma: a meta-analysis.Semantic proximity Read ↗

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